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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN965885 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint Kinase 1 (CHEK1) antibody
- Antibody type
- Polyclonal
- Antigen
- The antiserum was produced against synthesized non-phosphopeptide derived from human Chk1 around the phosphorylation site of serine 317 (S-S-SP-Q-P)
- Reactivity
- Human, Rat
- Host
- Rabbit
- Vial size
- 100 µg
- Concentration
- 100ug/100ul.
- Storage
- Store at -20°C/1 year.
Submitted references Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.
Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor.
DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system.
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains.
Zhang YW, Otterness DM, Chiang GG, Xie W, Liu YC, Mercurio F, Abraham RT
Molecular cell 2005 Sep 2;19(5):607-18
Molecular cell 2005 Sep 2;19(5):607-18
Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor.
Rocha S, Garrett MD, Campbell KJ, Schumm K, Perkins ND
The EMBO journal 2005 Mar 23;24(6):1157-69
The EMBO journal 2005 Mar 23;24(6):1157-69
DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system.
Clarke CA, Clarke PR
The Biochemical journal 2005 Jun 1;388(Pt 2):705-12
The Biochemical journal 2005 Jun 1;388(Pt 2):705-12
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains.
Yu X, Chen J
Molecular and cellular biology 2004 Nov;24(21):9478-86
Molecular and cellular biology 2004 Nov;24(21):9478-86
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