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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Immunocytochemistry [2]
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- Product number
- ADI-SPA-222-F - Provider product page
- Provider
- Enzo Life Sciences
- Product name
- alphaB Crystallin, mAb (1B6.1 3G4)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Protein G affinity purified. Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
- Isotype
- IgG
- Antibody clone number
- 1B6.1-3G4
Submitted references Selective and compartmentalized myelin expression of HspB5.
Expression of alpha B crystallin and BCL2 in patients with infiltrating ductal carcinoma.
ERK-regulated αB-crystallin induction by matrix detachment inhibits anoikis and promotes lung metastasis in vivo.
High expression of crystallin αB represents an independent molecular marker for unfavourable ovarian cancer patient outcome and impairs TRAIL- and cisplatin-induced apoptosis in human ovarian cancer cells.
Chemical and biological approaches synergize to ameliorate protein-folding diseases.
Elevated retina-specific expression of the small heat shock protein, alphaA-crystallin, is associated with photoreceptor protection in experimental uveitis.
Loop of Henle interaction with interstitial nodal spaces in the renal inner medulla.
The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation.
Quraishe S, Wyttenbach A, Matinyarare N, Perry VH, Fern R, O'Connor V
Neuroscience 2016 Mar 1;316:130-42
Neuroscience 2016 Mar 1;316:130-42
Expression of alpha B crystallin and BCL2 in patients with infiltrating ductal carcinoma.
Kim MS, Lee HW, Jun SY, Lee EH
International journal of clinical and experimental pathology 2015;8(8):8842-56
International journal of clinical and experimental pathology 2015;8(8):8842-56
ERK-regulated αB-crystallin induction by matrix detachment inhibits anoikis and promotes lung metastasis in vivo.
Malin D, Strekalova E, Petrovic V, Rajanala H, Sharma B, Ugolkov A, Gradishar WJ, Cryns VL
Oncogene 2015 Nov 5;34(45):5626-34
Oncogene 2015 Nov 5;34(45):5626-34
High expression of crystallin αB represents an independent molecular marker for unfavourable ovarian cancer patient outcome and impairs TRAIL- and cisplatin-induced apoptosis in human ovarian cancer cells.
Volkmann J, Reuning U, Rudelius M, Häfner N, Schuster T, Becker V Ros A, Weimer J, Hilpert F, Kiechle M, Dürst M, Arnold N, Schmalfeldt B, Meindl A, Ramser J
International journal of cancer 2013 Jun 15;132(12):2820-32
International journal of cancer 2013 Jun 15;132(12):2820-32
Chemical and biological approaches synergize to ameliorate protein-folding diseases.
Mu TW, Ong DS, Wang YJ, Balch WE, Yates JR 3rd, Segatori L, Kelly JW
Cell 2008 Sep 5;134(5):769-81
Cell 2008 Sep 5;134(5):769-81
Elevated retina-specific expression of the small heat shock protein, alphaA-crystallin, is associated with photoreceptor protection in experimental uveitis.
Rao NA, Saraswathy S, Wu GS, Katselis GS, Wawrousek EF, Bhat S
Investigative ophthalmology & visual science 2008 Mar;49(3):1161-71
Investigative ophthalmology & visual science 2008 Mar;49(3):1161-71
Loop of Henle interaction with interstitial nodal spaces in the renal inner medulla.
Pannabecker TL
American journal of physiology. Renal physiology 2008 Dec;295(6):F1744-51
American journal of physiology. Renal physiology 2008 Dec;295(6):F1744-51
The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation.
Kamradt MC, Chen F, Cryns VL
The Journal of biological chemistry 2001 May 11;276(19):16059-63
The Journal of biological chemistry 2001 May 11;276(19):16059-63
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of alpha B Crystallin: Lane 1: MW marker, Lane 2: alpha-Crystallin, Lane 3: alpha A Crystallin, Lane 4: alpha B Crystallin, Lane 5: alpha-Crystallin.
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of human Heart tissue stained with alpha B-Crystallin, mAb (1B6.1-3G4) at 10µg/ml.
