Tissue expression
Cell line expression
Protein structure
PDCD6
Programmed cell death 6ALG-2, PEF1B
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012]
Top validated antibodies |
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Proteintech Group | 12303-1-AP | 20 references | Polyclonal |
WB
EL
IP
IHC |
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antibodies-online | ABIN4948241 | 5 references | Monoclonal |
WB
EL
ICC
IHC |
|
Invitrogen Antibodies | PA5-76990 | Polyclonal |
WB
ICC
IP
IHC
OA
|
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Novus Biologicals | H00010016-M01 | 3 references | Monoclonal |
WB
EL
ICC
|
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LSBio | LS-B15517 | Polyclonal |
WB
ICC
IHC
|
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