600-401-981S

antibody from Rockland Immunochemicals, Inc.

Targeting: HSP90AA1 FLJ31884, Hsp89, Hsp90, HSP90N, HSPC1, HSPCA

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

600-401-981S

Provider

Rockland Immunochemicals, Inc.

Proper citation

Rockland Cat#600-401-981S, RRID:AB_2612820

Product name

Anti-Heat Shock Protein HSP 90-alpha acetyl specific K294 (RABBIT) Antibody - 600-401-981S

Antibody type

Polyclonal

Vial size

25 µl

References

Submitted references

MOF negatively regulates estrogen receptor α signaling via CUL4B-mediated protein degradation in breast cancer.

Zhang X, Yang Y, Li D, Wu Z, Liu H, Zhao Z, Zhu H, Xie F, Li X
Frontiers in oncology 2022;12:868866

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Corrigendum to "Hsp90 chaperone facilitates E2F1/2-dependent gene transcription in human breast cancer cells" [Eur. J. Cell Biol. 100 (2021) 151148].

Kotwal A, Suran S, Amere Subbarao S
European journal of cell biology 2021 Apr;100(3):151157

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A novel histone deacetylase 6 inhibitor improves myelination of Schwann cells in a model of Charcot-Marie-Tooth disease type 1A.

Ha N, Choi YI, Jung N, Song JY, Bae DK, Kim MC, Lee YJ, Song H, Kwak G, Jeong S, Park S, Nam SH, Jung SC, Choi BO
British journal of pharmacology 2020 Nov;177(22):5096-5113

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SIRT2 suppresses expression of inflammatory factors via Hsp90-glucocorticoid receptor signalling.

Sun K, Wang X, Fang N, Xu A, Lin Y, Zhao X, Nazarali AJ, Ji S
Journal of cellular and molecular medicine 2020 Jul;24(13):7439-7450

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The Role of Alcohol-Induced Golgi Fragmentation for Androgen Receptor Signaling in Prostate Cancer.

Manca S, Frisbie CP, LaGrange CA, Casey CA, Riethoven JM, Petrosyan A
Molecular cancer research : MCR 2019 Jan;17(1):225-237

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Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy.

Mo Z, Zhao X, Liu H, Hu Q, Chen XQ, Pham J, Wei N, Liu Z, Zhou J, Burgess RW, Pfaff SL, Caskey CT, Wu C, Bai G, Yang XL
Nature communications 2018 Mar 8;9(1):1007

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ATAT1 is essential for regulation of homeostasis-retaining cellular responses in corticotrophs along hypothalamic-pituitary-adrenal axis.

Nakakura T, Suzuki T, Torii S, Asano-Hoshino A, Nekooki-Machida Y, Tanaka H, Arisawa K, Nishijima Y, Susa T, Okazaki T, Kiuchi Y, Hagiwara H
Cell and tissue research 2017 Oct;370(1):169-178

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Histone Deacetylase 6-Controlled Hsp90 Acetylation Significantly Alters Mineralocorticoid Receptor Subcellular Dynamics But Not its Transcriptional Activity.

Jiménez-Canino R, Lorenzo-Díaz F, Jaisser F, Farman N, Giraldez T, Alvarez de la Rosa D
Endocrinology 2016 Jun;157(6):2515-32

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Requirement of HDAC6 for activation of Notch1 by TGF-β1.

Deskin B, Lasky J, Zhuang Y, Shan B
Scientific reports 2016 Aug 8;6:31086

Immunohistochemistry

Supportive validation

Submitted by

Rockland Immunochemicals, Inc. (provider)

Main image

Experimental details

Rockland's affinity purified anti-Hsp90 acetyl K294 antibody was used at 20 µg/ml to detect signal in a variety of tissues including multi-human, multi-brain and multi-cancer slides. This image shows moderate nuclear and granular cytoplasmic positive staining in human prostate carcinoma at 40X. Tissue was formalin-fixed and paraffin embedded. The image shows localization of the antibody as the precipitated red signal, with a hematoxylin purple nuclear counterstain. Personal Communi-cation, Tina Roush, LifeSpanBiosciences, Seattle, WA.

Validation comment

Immunohistochemistry