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Learn11-0625-42
antibody from Invitrogen Antibodies
Targeting: SELL
CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- 11-0625-42 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD62L (L-Selectin) Monoclonal Antibody (SK11), FITC, eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: This SK11 monoclonal antibody reacts with human and non-human primate CD62L (also known as L-selectin and LECAM). CD62L is expressed on neutrophils, monocytes, and subsets of T, B, and NK cells, as well as endothelial cells. This cell surface adhesion molecule binds glycolsylated, fucosylated and sulfated sialylated glycoproteins, including CD34, glycam-1, and MadCAM-1. These interactions mediate rolling of lymphocytes on activated endothelium at the sites of inflammation and homing of cells to the high endothelial venules (HEV) of peripheral lymphoid tissues.
- Conjugate
- Green dye
- Antibody clone number
- SK11
- Concentration
- 5 µL/Test
Submitted references Extracellular survivin up-regulates adhesion molecules on the surface of leukocytes changing their reactivity pattern.
Report on the Fifth International Workshop on Human Leukocyte Differentiation Antigens, Boston, November 3-7, 1993.
Lymphocyte activation and expression of the human leucocyte-endothelial cell adhesion molecule 1 (Leu-8/TQ1 antigen).
Mera S, Magnusson M, Tarkowski A, Bokarewa M
Journal of leukocyte biology 2008 Jan;83(1):149-55
Journal of leukocyte biology 2008 Jan;83(1):149-55
Report on the Fifth International Workshop on Human Leukocyte Differentiation Antigens, Boston, November 3-7, 1993.
Lanza F, Moretti S, Papa S, Malavasi F, Castoldi G
Haematologica 1994 Jul-Aug;79(4):374-86
Haematologica 1994 Jul-Aug;79(4):374-86
Lymphocyte activation and expression of the human leucocyte-endothelial cell adhesion molecule 1 (Leu-8/TQ1 antigen).
Bührer C, Berlin C, Thiele HG, Hamann A
Immunology 1990 Nov;71(3):442-8
Immunology 1990 Nov;71(3):442-8
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Staining of normal human peripheral blood cells with Anti-Human CD4 APC (Product # 17-0048-42) and Mouse IgG2a K Isotype Control FITC (Product # 11-4724-42) (left) or Anti-Human/NHP CD62L (L-selectin) FITC (right). Cells in the lymphocyte gate were used for analysis.
- Conjugate
- Green dye
