Tissue expression
Cell line expression
Protein structure
SELL
Selectin LCD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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| Invitrogen Antibodies | 15 references | Monoclonal |
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| Biorbyt | Monoclonal |
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| LSBio | Polyclonal |
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| antibodies-online | 1 references | Polyclonal |
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| Antibodies.com | Monoclonal |
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