PTPN13

gene product
PTP-BAS, PTP-BL, PTP1E, PTPL1
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008]
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188 antibodies from 25 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Abnova Corporation
3 antibodies
Novus Biologicals
5 antibodies
Acris Antibodies GmbH
10 antibodies
antibodies-online
68 antibodies
Boster Biological Technology
1 antibody
OriGene
5 antibodies
R&D Systems
2 antibodies
LifeSpan BioSciences, Inc.
39 antibodies
Biorbyt
7 antibodies
Invitrogen Antibodies
4 antibodies
Enzo Life Sciences
1 antibody
United States Biological
9 antibodies
Spring Bioscience
4 antibodies
ProSci
3 antibodies
St John's Laboratory
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
NovoPro Bioscience Inc.
1 antibody
RayBiotech, Inc.
3 antibodies
MyBioSource
2 antibodies
Abgent
1 antibody
Creative Diagnostics
1 antibody
GeneTex
1 antibody
GenWay
1 antibody
Sigma-Aldrich
2 antibodies