BS3004

antibody from Bioworld Technology, Inc

Targeting: ZFP36L1 Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B

Immunohistochemistry

Antibody data

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Validation data

Product number: BS3004 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS3004, RRID:AB_1663099
Product name: TIS11B (D88) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 50-100 of Human TIS11B.
Description: TIS11B (tetradecanoyl phorbol acetate-inducible sequence 11b), also known as ZFP36L1, BRF1 (butyrate response factor 1), ERF1 (EGF response factor 1), cMG1, Berg36 or RNF162B, is a member of the tristetraprolin family. Tristetraprolin (TTP), or TIS11, is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating Cys-His motif. TIS11B is an mRNA binding protein and is known to interact with the 3'-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

ZFP36L1 protein structure - BS3004 shown in red.