ZFP36L1

This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Description

ZFP36 ring finger protein like 1

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Cancer-related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

14 (68787660 - 68796253)

Ensembl ID

ENSG00000185650  (ver. 103.38)

Orthologs

Mouse Zfp36l1: ENSMUSG00000021127

UniProt

Q07352

neXtProt

NX_Q07352

Human splice variants
Mouse splice variants

Protein structure