KCND1

This gene encodes a multipass membrane protein that comprises the pore subunit of the voltage-gated A-type potassium channel, which functions in the repolarization of membrane action potentials. Activity of voltage-gated potassium channels is important in a number of physiological processes, among them the regulation of neurotransmitter release, heart rate, insulin secretion, and smooth muscle contraction. [provided by RefSeq, Aug 2013]

Description

Potassium voltage-gated channel subfamily D member 1

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Intracellular, Membrane

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Transporters
Voltage-gated ion channels

Chromosome

X:p11.23 (48961378 - 48971844)

Ensembl ID

ENSG00000102057  (ver. 103.38)

Orthologs

Mouse Kcnd1: ENSMUSG00000009731

UniProt

Q9NSA2

neXtProt

NX_Q9NSA2

Human splice variants
Mouse splice variants