DPABH-10121

antibody from Creative Diagnostics

Targeting: DCC IGDCC1, NTN1R1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-10121

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-10121, RRID:AB_2516886

Product name

Rabbit Anti-Human DCC Polyclonal Antibody

Antibody type

Polyclonal

Description

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _L

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C. Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.