ABIN401410

antibody from antibodies-online

Targeting: SMAD4 DPC4, MADH4

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN401410

Provider

antibodies-online

Product name

anti-SMAD Family Member 4 (SMAD4) (C-Term) antibody

Antibody type

Polyclonal

Description

Affinity chromatography

Reactivity

Human, Mouse, Xenopus

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

0.1 mg

Storage

-20°C

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Smad4 is critical for self-renewal of hematopoietic stem cells.

Karlsson G, Blank U, Moody JL, Ehinger M, Singbrant S, Deng CX, Karlsson S
The Journal of experimental medicine 2007 Mar 19;204(3):467-74

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Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression.

Wang LH, Kim SH, Lee JH, Choi YL, Kim YC, Park TS, Hong YC, Wu CF, Shin YK
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Jan 1;13(1):102-10

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Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling.

Lim SK, Hoffmann FM
Proceedings of the National Academy of Sciences of the United States of America 2006 Dec 5;103(49):18580-5

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Regulation of Smad4 sumoylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1.

Liang M, Melchior F, Feng XH, Lin X
The Journal of biological chemistry 2004 May 28;279(22):22857-65

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Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation.

Roelen BA, Cohen OS, Raychowdhury MK, Chadee DN, Zhang Y, Kyriakis JM, Alessandrini AA, Lin HY
American journal of physiology. Cell physiology 2003 Oct;285(4):C823-30