SMAD4

gene product
DPC4, MADH4
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009]
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776 antibodies from 37 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
262 antibodies
Novus Biologicals
21 antibodies
GeneTex
9 antibodies
Invitrogen Antibodies
11 antibodies
Cell Signaling Technology, Inc
3 antibodies
Biorbyt
69 antibodies
Acris Antibodies GmbH
17 antibodies
Abnova Corporation
26 antibodies
OriGene
18 antibodies
Abgent
11 antibodies
NSJ Bioreagents
7 antibodies
R&D Systems
12 antibodies
Affinity Biosciences
6 antibodies
Aviva Systems Biology
9 antibodies
Proteintech Group
3 antibodies
NovoPro Bioscience Inc.
12 antibodies
Boster Biological Technology
5 antibodies
St John's Laboratory
4 antibodies
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
2 antibodies
ProSci
4 antibodies
Arigo
3 antibodies
RabMAbs
3 antibodies
Antibodies.com
1 antibody
Creative Diagnostics
7 antibodies
MyBioSource
16 antibodies
FabGennix
12 antibodies
Everest Biotech
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
United States Biological
200 antibodies
ABEOMICS Inc.
2 antibodies
EMD Millipore
5 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
RayBiotech, Inc.
3 antibodies
Abiocode, Inc.
1 antibody
Sigma-Aldrich
5 antibodies
Abbexa
3 antibodies