abx200209

antibody from Abbexa

Targeting: CD27 S152, TNFRSF7, Tp55

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx200209

Provider

Abbexa

Product name

CD27 Antigen / TNFRSF7 (CD27) Antibody (PE)

Antibody type

Monoclonal

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Reactivity

Human, Sheep, Simian

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG

Vial size

100 tests

Storage

Aliquot and store in the dark at 2°C to 8°C. Avoid exposure to light.