AMM01529G

antibody from Leading Biology

Targeting: CD27 S152, TNFRSF7, Tp55

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

AMM01529G

Provider

Leading Biology

Product name

CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody - With BSA and Azide

Antibody type

Monoclonal

Description

Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

Reactivity

Human

Host

Mouse

Antibody clone number

203.6

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.