RA0778

antibody from Oursmab

Targeting: CD27 S152, TNFRSF7, Tp55

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0778

Provider

Oursmab

Product name

Boserolimab (Biosimilar Reference Antibody) (TNFRSF7)

Antibody type

Monoclonal

Description

Boserolimab (also known as MK-5890) is a humanized monoclonal antibody designed to act as an agonistic immune modulator. Its primary function is to specifically target and bind to the CD27 receptor. By engaging CD27, Boserolimab provides a co-stimulatory signal to T cells, mimicking the effect of the natural ligand, CD70. This co-stimulation is intended to enhance T cell mediated immune responses, promoting the proliferation and activation of cytotoxic T lymphocytes (CTLs). This mechanism makes it a candidate for cancer immunotherapy, where the goal is to boost the body's immune attack against malignant cells.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Boserolimab (Biosimilar Reference Antibody) (TNFRSF7)-RA0778-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Boserolimab (Biosimilar Reference Antibody) (TNFRSF7)-RA0778 in a linear range of 3.91-125 ng/mL.