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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 348509 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#348509, RRID:AB_2562927
- Product name
- PerCP/Cy5.5 anti-human CD144 (VE-Cadherin)
- Antibody type
- Monoclonal
- Antigen
- 0
- Description
- CD144, also known as VE-cadherin and cadherin-5, is a 140 kD glycoprotein which is composed of 5 extracellular cadherin repeats and a highly conserved cytoplasmic tail region. It is a calcium-dependent transmembrane cell-cell adhesion molecule localized at the intercellular boundaries of endothelial cells, hematopoietic stem cells, and perineurial cells. It functions as a classic cadherin by mediating homophilic adhesion and functions as a plasma membrane attachment site for the cytoskeleton. CD144 is thought to play a role in vascular development, permeability, and remodeling.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antibody clone number
- BV9
- Vial size
- 25 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human umbilical vein endothelial cells (HUVEC) were stained with CD144 (clone BV9) PerCP/Cy5.5 (filled histogram) or mouse IgG2a, κ PerCP/Cy5.5 isotype control (open histogram).
