Tissue expression
Cell line expression
Protein structure
CDH5
Cadherin 57B4, CD144
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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OriGene | ![]() |
1 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
23 references | Polyclonal |
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Novus Biologicals | ![]() |
2 references | Monoclonal |
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Boster Biological Technology | ![]() |
2 references | Polyclonal |
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antibodies-online | ![]() |
6 references | Monoclonal |
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