348502

antibody from BioLegend

Targeting: CDH5 7B4, CD144

Western blot

Immunocytochemistry

Immunoprecipitation

Antibody data

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Validation data

Product number: 348502 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#348502, RRID:AB_10588267
Product name: Purified anti-human CD144 (VE-Cadherin)
Antibody type: Monoclonal
Antigen: CD144
Description: CD144, also known as VE-cadherin and cadherin-5, is a 140 kD glycoprotein which is composed of 5 extracellular cadherin repeats and a highly conserved cytoplasmic tail region. It is a calcium-dependent transmembrane cell-cell adhesion molecule localized at the intercellular boundaries of endothelial cells, hematopoietic stem cells, and <a href=\http://www.copewithcytokines.de/cope.cgi?key=perineurial%20cells">perineurial cells</a>. It functions as a classic cadherin by mediating homophilic adhesion and functions as a plasma membrane attachment site for the cytoskeleton. CD144 is thought to play a role in vascular development, permeability, and remodeling.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C.

CDH5 protein structure - 348502 shown in red.