348504

antibody from BioLegend
Targeting: CDH5 7B4, CD144
Provider product page for 348504
Western blot
Immunocytochemistry
Immunoprecipitation
Flow cytometry
Blocking/Neutralizing

Antibody data

Product number
348504 - Provider product page
Provider
BioLegend
Product name
LEAF™ Purified anti-human CD144 (VE-Cadherin) [BV9]
Antibody type
Monoclonal
Antigen
CD144
Description
CD144, also known as VE-cadherin and cadherin-5, is a 140 kD glycoprotein which is composed of 5 extracellular cadherin repeats and a highly conserved cytoplasmic tail region. It is a calcium-dependent transmembrane cell-cell adhesion molecule localized at the intercellular boundaries of endothelial cells, hematopoietic stem cells, and perineurial cells. It functions as a classic cadherin by mediating homophilic adhesion and functions as a plasma membrane attachment site for the cytoskeleton. CD144 is thought to play a role in vascular development, permeability, and remodeling.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
500 µg
Concentration
1 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
CDH5 protein structure - 348504 shown in red.