348505

antibody from BioLegend

Targeting: CDH5 7B4, CD144

Antibody data

Submit

Validation data

Product number: 348505 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#348505, RRID:AB_2260350
Product name: PE anti-human CD144 (VE-Cadherin)
Antibody type: Monoclonal
Antigen: CD144
Description: CD144, also known as VE-cadherin and cadherin-5, is a 140 kD glycoprotein which is composed of 5 extracellular cadherin repeats and a highly conserved cytoplasmic tail region. It is a calcium-dependent transmembrane cell-cell adhesion molecule localized at the intercellular boundaries of endothelial cells, hematopoietic stem cells, and <a href=\http://www.copewithcytokines.de/cope.cgi?key=perineurial%20cells">perineurial cells</a>. It functions as a classic cadherin by mediating homophilic adhesion and functions as a plasma membrane attachment site for the cytoskeleton. CD144 is thought to play a role in vascular development, permeability, and remodeling.
Reactivity: Human
Host: Mouse
Conjugate: Yellow dye
Isotype: IgG
Vial size: 25 tests
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

CDH5 protein structure - 348505 shown in red.