Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- MAB996 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal PSGL-1/CD162 Antibody
- Antibody type
- Monoclonal
- Description
- IgM-specific Affinity-purified from hybridoma culture supernatant. Detects human PSGL-1/CD162. Recognizes sLex-bearing core 2 O-glycan stuctures. It does not recognize sLex on an extended core 1 O-glycan. The sLex-bearing, core 2 O-glycan structure decorates the P-Selectin ligand PSGL-1, and the presence of this glycan structure is required for high affinity P-Selectin binding (1). This antibody stains human and canine leukocytes but does not recognize monkey, mouse, rabbit, porcine, feline or bovine leukocytes.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgM
- Vial size
- 500 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Up-Regulated Expression of Matrix Metalloproteinases in Endothelial Cells Mediates Platelet Microvesicle-Induced Angiogenesis.
Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1.
P-selectin glycoprotein ligand-1 regulates chemokine-dependent leukocyte recruitment in colonic ischemia-reperfusion.
Sun C, Feng SB, Cao ZW, Bei JJ, Chen Q, Zhao WB, Xu XJ, Zhou Z, Yu ZP, Hu HY
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(6):2319-2332
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(6):2319-2332
Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1.
Banks JM, Herman CT, Bailey RC
PloS one 2013;8(11):e78988
PloS one 2013;8(11):e78988
P-selectin glycoprotein ligand-1 regulates chemokine-dependent leukocyte recruitment in colonic ischemia-reperfusion.
Santen S, Schramm R, Menger MD, Wang Y, Jeppsson B, Thorlacius H
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2007 Nov;56(11):452-8
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2007 Nov;56(11):452-8
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