SELPLG

gene product
CD162, PSGL-1
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]
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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
90 antibodies
antibodies-online
326 antibodies
R&D Systems
19 antibodies
Invitrogen Antibodies
17 antibodies
GeneTex
14 antibodies
Boster Biological Technology
2 antibodies
BioLegend
12 antibodies
Abnova Corporation
9 antibodies
Bioworld Technology, Inc
1 antibody
LifeSpan BioSciences, Inc.
145 antibodies
NovoPro Bioscience Inc.
9 antibodies
Affinity Biosciences
1 antibody
Acris Antibodies GmbH
16 antibodies
OriGene
10 antibodies
Biorbyt
30 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Biolabs
81 antibodies
Antibodies.com
5 antibodies
St John's Laboratory
2 antibodies
NSJ Bioreagents
1 antibody
Aviva Systems Biology
10 antibodies
RabMAbs
2 antibodies
Arigo
4 antibodies
ProSci
3 antibodies
United States Biological
43 antibodies