Tissue expression
Cell line expression

SELPLG

gene product
CD162, PSGL-1 
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]
More gene data

Antibodies

 

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1142 antibodies from 40 providers.

Antibody properties

Applications

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
155 antibodies
R&D Systems
27 antibodies
antibodies-online
326 antibodies
NSJ Bioreagents
3 antibodies
Proteintech Group
1 antibody
BioLegend
19 antibodies
LifeSpan BioSciences, Inc.
177 antibodies
OriGene
12 antibodies
GeneTex
14 antibodies
Invitrogen Antibodies
36 antibodies
Abnova Corporation
9 antibodies
Boster Biological Technology
3 antibodies
Bioworld Technology, Inc
1 antibody
Acris Antibodies GmbH
16 antibodies
Cusabio Biotech Co., Ltd
5 antibodies
NovoPro Bioscience Inc.
9 antibodies
Affinity Biosciences
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
Biorbyt
30 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Antibodies.com
5 antibodies
St John's Laboratory
2 antibodies
Aviva Systems Biology
10 antibodies
RabMAbs
2 antibodies
Arigo
4 antibodies
ProSci
3 antibodies
United States Biological
43 antibodies
eBioscience, An Affymetrix Company
9 antibodies
EMD Millipore
2 antibodies
Creative Diagnostics
7 antibodies
Miltenyi Biotec
31 antibodies
Creative Biolabs
111 antibodies
Abgent
5 antibodies
GenWay
9 antibodies
Abbexa
10 antibodies
MyBioSource
4 antibodies
RayBiotech, Inc.
4 antibodies
Leading Biology
4 antibodies
Sino Biological Inc.
2 antibodies