orb385968

antibody from Biorbyt

Targeting: SELPLG CD162, PSGL-1

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

orb385968

Provider

Biorbyt

Product name

CD162 Antibody / P selectin glycoprotein ligand 1 / PSGL-1

Antibody type

Monoclonal

Description

P selectin glycoprotein ligand 1 (PSGL-1), also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antibody clone number

PSGL1/1601

Vial size

20 ug

Storage

Store the PSGL-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).