Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- 328805 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#328805, RRID:AB_2185244
- Product name
- PE anti-human CD162
- Antibody type
- Monoclonal
- Antigen
- PSGL-1 transfected murine 300.19 pre B-cell line
- Description
- CD162, also known as p-selectin glycoprotein ligand-1 (PSGL-1), is a 120 - 220 kD, mucin-like type I transmembrane glycoprotein. CD162 binds to CD62P (P-Selectin), CD62E (E-Selectin) and CD62L (L-Selectin). The interactions between P-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) mediate the earliest "rolling" of leukocytes on the lumenal surface of activated endothelium, and the interaction between leukocytes and activated platelets or other leukocytes found at sites of inflammation. CD162 is expressed on neutrophils, monocytes, and most lymphocytes including NK and T cells but PSGL-1 stains B cells at significantly lower levels than other cell types.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Adaptive mutations in the genomes of enterovirus 71 strains following infection of mouse cells expressing human P-selectin glycoprotein ligand-1.
Heterogeneity of human monocytes: an optimized four-color flow cytometry protocol for analysis of monocyte subsets.
Miyamura K, Nishimura Y, Abo M, Wakita T, Shimizu H
The Journal of general virology 2011 Feb;92(Pt 2):287-91
The Journal of general virology 2011 Feb;92(Pt 2):287-91
Heterogeneity of human monocytes: an optimized four-color flow cytometry protocol for analysis of monocyte subsets.
Tallone T, Turconi G, Soldati G, Pedrazzini G, Moccetti T, Vassalli G
Journal of cardiovascular translational research 2011 Apr;4(2):211-9
Journal of cardiovascular translational research 2011 Apr;4(2):211-9
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes stained with KPL-1 PE
- Conjugate
- Yellow dye