Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 14580-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14580-1-AP, RRID:AB_10639524
- Product name
- Perforin antibody
- Antibody type
- Polyclonal
- Description
- Perforin antibody (Cat. #14580-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma.
The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer.
Perforin and granzyme A release as novel tool to measure NK cell activation in chickens.
Schisandrin B induces HepG2 cells pyroptosis by activating NK cells mediated anti-tumor immunity.
Tannins in Terminalia bellirica inhibits hepatocellular carcinoma growth via re-educating tumor-associated macrophages and restoring CD8(+)T cell function.
The Role of Tim-3 on dNK Cells Dysfunction During Abnormal Pregnancy With Toxoplasma gondii Infection.
Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune checkpoint blocking combination therapy via activating cGAS/STING signaling in gastric cancer cells.
VEGF165b augments NK92 cytolytic activity against human K562 leukemia cells by upregulating the levels of perforin and granzyme B via the VEGR1-PLC pathway.
Characterization of cytotoxicity-related gene expression in response to virulent Marek's disease virus infection in the bursa of Fabricius.
Liang Y, He S, Liu Q, Liu T, Tan Y, Peng T, Huang C, Lu X, Zheng S
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119781
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119781
The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer.
Ge W, Meng L, Cao S, Hou C, Zhu X, Huang D, Li Q, Peng Y, Jiang K
Journal of immunology research 2023;2023:6891636
Journal of immunology research 2023;2023:6891636
Perforin and granzyme A release as novel tool to measure NK cell activation in chickens.
Ijaz A, Broere F, Rutten VPMG, Jansen CA, Veldhuizen EJA
Developmental and comparative immunology 2023 Dec;149:105047
Developmental and comparative immunology 2023 Dec;149:105047
Schisandrin B induces HepG2 cells pyroptosis by activating NK cells mediated anti-tumor immunity.
Song A, Ding T, Wei N, Yang J, Ma M, Zheng S, Jin H
Toxicology and applied pharmacology 2023 Aug 1;472:116574
Toxicology and applied pharmacology 2023 Aug 1;472:116574
Tannins in Terminalia bellirica inhibits hepatocellular carcinoma growth via re-educating tumor-associated macrophages and restoring CD8(+)T cell function.
Chang Z, Zhang Q, Hu Q, Liu Y, Zhang L, Liu R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113543
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113543
The Role of Tim-3 on dNK Cells Dysfunction During Abnormal Pregnancy With Toxoplasma gondii Infection.
Li T, Cui L, Xu X, Zhang H, Jiang Y, Ren L, Yang C, Liu X, Hu X
Frontiers in cellular and infection microbiology 2021;11:587150
Frontiers in cellular and infection microbiology 2021;11:587150
Targeting MUS81 promotes the anticancer effect of WEE1 inhibitor and immune checkpoint blocking combination therapy via activating cGAS/STING signaling in gastric cancer cells.
Li C, Shen Q, Zhang P, Wang T, Liu W, Li R, Ma X, Zeng X, Yin Y, Tao K
Journal of experimental & clinical cancer research : CR 2021 Oct 8;40(1):315
Journal of experimental & clinical cancer research : CR 2021 Oct 8;40(1):315
VEGF165b augments NK92 cytolytic activity against human K562 leukemia cells by upregulating the levels of perforin and granzyme B via the VEGR1-PLC pathway.
Wang X, Liang C, Xia W, Guo C, Niu Z, Zhu W, Zhang H
Molecular immunology 2020 Dec;128:41-46
Molecular immunology 2020 Dec;128:41-46
Characterization of cytotoxicity-related gene expression in response to virulent Marek's disease virus infection in the bursa of Fabricius.
Chen CY, Xie QM, Xue Y, Ji J, Chang S, Ma JY, Bi YZ
Research in veterinary science 2013 Jun;94(3):496-503
Research in veterinary science 2013 Jun;94(3):496-503
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The Perforin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Perforin. This antibody recognizes human, mouse antigen. The Perforin antibody has been validated for the following applications: ELISA, WB analysis.