PRF1

gene product
HPLH2, P1, PFP
This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
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566 antibodies from 40 providers.

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Novus Biologicals
34 antibodies
Enzo Life Sciences
3 antibodies
GeneTex
8 antibodies
antibodies-online
147 antibodies
Antibodies.com
2 antibodies
LifeSpan BioSciences, Inc.
85 antibodies
Biorbyt
37 antibodies
Abnova Corporation
10 antibodies
BioLegend
48 antibodies
Bioworld Technology, Inc
1 antibody
St John's Laboratory
2 antibodies
Affinity Biosciences
1 antibody
Proteintech Group
1 antibody
Invitrogen Antibodies
18 antibodies
NSJ Bioreagents
4 antibodies
OriGene
15 antibodies
R&D Systems
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
Boster Biological Technology
2 antibodies
Cell Signaling Technology, Inc
2 antibodies
NovoPro Bioscience Inc.
2 antibodies
Acris Antibodies GmbH
14 antibodies
Creative Biolabs
12 antibodies
GenWay
6 antibodies
Abbexa
8 antibodies
ProSci
3 antibodies
Arigo
2 antibodies
Aviva Systems Biology
2 antibodies
Atlas Antibodies
1 antibody
Miltenyi Biotec
14 antibodies
United States Biological
27 antibodies
MyBioSource
12 antibodies
Abiocode, Inc.
4 antibodies
RabMAbs
1 antibody
Signalway Antibody LLC
1 antibody
Creative Diagnostics
8 antibodies
eBioscience, An Affymetrix Company
12 antibodies
Abgent
1 antibody
Sigma-Aldrich
2 antibodies