Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PB9155 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Perforin/PRF1 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for PERFORIN/PRF1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. PERFORIN/PRF1 information: Molecular Weight: 61377 MW; Subcellular Localization: Cytoplasmic granule lumen. Secreted. Cell membrane; Multi-pass membrane protein. Endosome lumen. Stored in cytoplasmic granules of cytolytic T-lymphocytes and secreted into the cleft between T-lymphocyte and target cell. Inserts into the cell membrane of target cells and forms pores. Membrane insertion and pore formation requires a major conformation change. May be taken up via endocytosis involving clathrin-coated vesicles and accumulate in a first time in large early endosomes.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Natural Killer Cell Phenotype and Functionality Affected by Exposure to Extracellular Survivin and Lymphoma-Derived Exosomes.
Ferguson Bennit HR, Gonda A, Kabagwira J, Oppegard L, Chi D, Licero Campbell J, De Leon M, Wall NR
International journal of molecular sciences 2021 Jan 27;22(3)
International journal of molecular sciences 2021 Jan 27;22(3)
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Supportive validation
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- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-Perforin Picoband antibody, PB9155-1.jpgAll lanes: Anti Perforin (PB9155) at 0.5ug/mlWB: Recombinant Human Perforin Protein 0.5ngPredicted bind size: 40KDObserved bind size: 40KD
- Additional image