Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN187239 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Perforin 1 (Pore Forming Protein) (PRF1) (AA 189-360) antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant mouse perforin fragment encompassing 172 amino acid residues (His189-Cys360) which contains the membrane binding domain and part of the EGF-type cysteine-rich domain.Mouse myeloma (P3U/I) x immunized SD rat spleen cells.
- Description
- Ascites
- Reactivity
- Human, Mouse
- Host
- Rat
- Epitope
- AA 189-360
- Isotype
- IgG
- Antibody clone number
- KM585 (P1-8)
- Vial size
- 0.1 mL
- Storage
- 4°C
Submitted references Functional assessment of perforin C2 domain mutations illustrates the critical role for calcium-dependent lipid binding in perforin cytotoxic function.
Stimulatory effects of CpG oligodeoxynucleotide on dendritic cell-based immunotherapy of colon cancer in CEA/HLA-A2 transgenic mice.
IL-15-induced CD8+CD122+ T cells increase antibacterial and anti-tumor immune responses: implications for immune function in aged mice.
Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B).
Urrea Moreno R, Gil J, Rodriguez-Sainz C, Cela E, LaFay V, Oloizia B, Herr AB, Sumegi J, Jordan MB, Risma KA
Blood 2009 Jan 8;113(2):338-46
Blood 2009 Jan 8;113(2):338-46
Stimulatory effects of CpG oligodeoxynucleotide on dendritic cell-based immunotherapy of colon cancer in CEA/HLA-A2 transgenic mice.
Saha A, Bhattacharya-Chatterjee M, Foon KA, Celis E, Chatterjee SK
International journal of cancer. Journal international du cancer 2009 Feb 15;124(4):877-88
International journal of cancer. Journal international du cancer 2009 Feb 15;124(4):877-88
IL-15-induced CD8+CD122+ T cells increase antibacterial and anti-tumor immune responses: implications for immune function in aged mice.
Motegi A, Kinoshita M, Inatsu A, Habu Y, Saitoh D, Seki S
Journal of leukocyte biology 2008 Oct;84(4):1047-56
Journal of leukocyte biology 2008 Oct;84(4):1047-56
Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B).
Araki Y, Fann M, Wersto R, Weng NP
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 15;180(12):8102-8
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 15;180(12):8102-8
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