ABIN187239

antibody from antibodies-online

Targeting: PRF1 HPLH2, P1, PFP

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN187239

Provider

antibodies-online

Product name

anti-Perforin 1 (Pore Forming Protein) (PRF1) (AA 189-360) antibody

Antibody type

Monoclonal

Antigen

Recombinant mouse perforin fragment encompassing 172 amino acid residues (His189-Cys360) which contains the membrane binding domain and part of the EGF-type cysteine-rich domain.Mouse myeloma (P3U/I) x immunized SD rat spleen cells.

Description

Ascites

Reactivity

Human, Mouse

Host

Rat

Epitope

AA 189-360

Isotype

IgG

Antibody clone number

KM585 (P1-8)

Vial size

0.1 mL

Storage

4°C

References

Submitted references

Functional assessment of perforin C2 domain mutations illustrates the critical role for calcium-dependent lipid binding in perforin cytotoxic function.

Urrea Moreno R, Gil J, Rodriguez-Sainz C, Cela E, LaFay V, Oloizia B, Herr AB, Sumegi J, Jordan MB, Risma KA
Blood 2009 Jan 8;113(2):338-46

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Stimulatory effects of CpG oligodeoxynucleotide on dendritic cell-based immunotherapy of colon cancer in CEA/HLA-A2 transgenic mice.

Saha A, Bhattacharya-Chatterjee M, Foon KA, Celis E, Chatterjee SK
International journal of cancer. Journal international du cancer 2009 Feb 15;124(4):877-88

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IL-15-induced CD8+CD122+ T cells increase antibacterial and anti-tumor immune responses: implications for immune function in aged mice.

Motegi A, Kinoshita M, Inatsu A, Habu Y, Saitoh D, Seki S
Journal of leukocyte biology 2008 Oct;84(4):1047-56

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Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B).

Araki Y, Fann M, Wersto R, Weng NP
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 15;180(12):8102-8