SM1847LE

antibody from Acris Antibodies GmbH

Targeting: TNFSF10 Apo-2L, CD253, TL2, TRAIL

Flow cytometry (Recommended by provider)

Functional assay (Supportive data in Antibodypedia)

Antibody Data

Product number

SM1847LE

Provider

Acris Antibodies GmbH

Product name

anti CD253 / TRAIL (95-281)

Antibody type

Monoclonal

Antigen

Recombinant soluble fragment (aa 95-281) of human TRAIL

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

2E5

Vial size

0.1 mg

Concentration

1.0 mg/ml

Functional assay

Supportive validation

Submitted by

Acris Antibodies GmbH (provider)

Main image

Experimental details

Apoptosis induced in JURKAT human T cell leukemia cell line by soluble recombinant human TRAIL is completely blocked by anti-human TRAIL (2E5). The neutralizing activity of the antibody 2E5 has been confirmed with various sources of soluble recombinant human TRAIL.A - mediumB - recombinant TRAILC - recombinant TRAIL + anti-human TRAIL (2E5; 0.06 μg/ml)D - recombinant TRAIL + anti-human TRAIL (2E5; 0.24 μg/ml)E - recombinant TRAIL + Isotype mouse IgG1 controlE - recombinant TRAIL + Isotype mouse IgG1 control