BS60933

antibody from Bioworld Technology, Inc
Targeting: TNFSF10 Apo-2L, CD253, TL2, TRAIL
Provider product page for BS60933

Antibody data

Product number
BS60933 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TNFSF10 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human TNFSF10.
Description
Proteins belonging to the tumor necrosis factor (TNF) superfamily are potent mediators of the inflammation and immune systems. Members of the TNF superfamily include TNFÉÇ, lymphotoxin ÉÇ (LTÉÇ), CD40L, CD30L, CD27L, Ox40L, 4-1BBL and FAS-L (Apo-1). Most TNF family members are type II transmembrane proteins that are proteolytically processed at their carboxy-terminal extracellular domain to form a soluble homotrimeric molecule. The extracellular domain of an additional TNF family member, designated TNF-related apoptosis-inducing ligand (TRAIL) or Apo-2L, exhibits 14-28% homology with other members of the TNF family. Like soluble FAS-L, soluble TRAIL will induce apoptosis. The morphological and cellular changes caused by the introduction of soluble TRAIL to Jurkat cells are indistinguishable from those caused by the introduction of soluble FAS-L. Unlike FAS-L, whose expression is more or less restricted to activated T cells, significant levels of TRAIL are observed in many tissues and it is constitutively expressed by some cell lines.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TNFSF10 protein structure - BS60933 shown in red.