SM1847LE

antibody from OriGene

Targeting: TNFSF10 Apo-2L, CD253, TL2, TRAIL

Flow cytometry (Data presented on provider website)

Functional assay (Data presented on provider website)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

SM1847LE

Provider

OriGene

Product name

TRAIL (TNFSF10) (95-281) mouse monoclonal antibody, clone 2E5, Low Endotoxin

Antibody type

Monoclonal

Description

TRAIL (TNFSF10) (95-281) mouse monoclonal antibody, clone 2E5, Low Endotoxin

Host

Mouse

Conjugate

Unconjugated

Epitope

TNFSF10

Isotype

IgG

Antibody clone number

2E5

Vial size

100 µg

Concentration

1.0 mg/ml

Other assay

Supportive validation

Submitted by

OriGene (provider)

Main image

Experimental details

Apoptosis induced in JURKAT human T cell leukemia cell line by soluble recombinant human TRAIL is completely blocked by anti-human TRAIL (2E5). The neutralizing activity of the antibody 2E5 has been confirmed with various sources of soluble recombinant human TRAIL. A - medium B - recombinant TRAIL C - recombinant TRAIL + anti-human TRAIL (2E5; 0.06 ug/ml) D - recombinant TRAIL + anti-human TRAIL (2E5; 0.24 ug/ml) E - recombinant TRAIL + Isotype mouse IgG1 controlE - recombinant TRAIL + Isotype mouse IgG1 control

Validation comment

Assay