27064-1-AP

antibody from Proteintech Group

Targeting: TNFSF10 Apo-2L, CD253, TL2, TRAIL

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

27064-1-AP

Provider

Proteintech Group

Product name

TRAIL antibody

Antibody type

Polyclonal

Description

KD/KO validated TRAIL antibody (Cat. #27064-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

HIF-activated priming of TRAIL-induced cell death determines epigenetic vulnerability in kidney cancer.

Wang Y, Xiong Y, Liu S, Bao L, Qiu X, Korboukh I, Song X, Toffessi Tcheuyap V, Wu S, Chen M, Brugarolas J, Jin J, Wang Y, Luo W
Cell reports. Medicine 2026 Mar 17;7(3):102630

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Aging-dependent expression of vascular endothelial growth factor receptor-1 is associated with T-cell immune senescence in carotid atherosclerosis.

Zhang X, Wu S, Lu T, Li J, Cui S, Liu Z, Xie W, Xu R, Wang Y, Li W, Jiao L, Wang T
Brain circulation 2026 Jan-Mar;12(1):31-41

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Integrative analysis and experimental validation unveil TNFSF10 as a key PANoptosis inducer driving preeclampsia pathogenesis.

Mei Z, Li L, Chen J, Yang S, Li Y, Li X, Li M, Chen M, Kong R, Zhao Y, Zhao K, McClements L, Zhang H, Liu C
International immunopharmacology 2026 Apr 15;175:116401

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Endothelial TIE2 Mutation Induced Contraction Deficiency of Vascular Smooth Muscle Cells via Phenotypic Transition Regulation in Venous Malformations.

Du Z, Yu F, You YH, Zhao ZY, Tian ZW, Xiao M, Wang YA
International journal of medical sciences 2025;22(10):2518-2532

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Identification of biomarkers for the diagnosis of type 2 diabetes mellitus with metabolic associated fatty liver disease by bioinformatics analysis and experimental validation.

Wu G, Wu S, Xiong T, Yao Y, Qiu Y, Meng L, Chen C, Yang X, Liang X, Qin Y
Frontiers in endocrinology 2025;16:1512503

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Improving Targeted Delivery and Antitumor Efficacy of TRAIL through Fusion with a B7H3-Antagonistic Affibody.

Lu X, Zhan X, Xia G, Wang F, Lv M, Liu R, Liu Y, Zi C, Li G, Wang R, Li J, Yuan F, Jia D
Molecular pharmaceutics 2025 Jan 6;22(1):284-294

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Tumor-Specific Delivery of Nanomedicines via a Nutrient Sensing-Driven Pathway Mediated by Niemann-Pick C1-Like 1.

Miao G, Hou M, He Y, Peng W, Xu M, Shang Z, Zhao X, Wang X, Hu J, Liu S, Wang X
ACS nano 2025 Dec 9;19(48):40828-40849

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Multi-omics characterization of autophagy-related molecular features in intrahepatic cholestasis of pregnancy†.

Tang M, Luo M, Zhang L, Xiong L, Gong X, Zhou X, Yang J, Wang P, Zhao Z, Wu S, Xing S, Cai J, Yang X
Biology of reproduction 2025 Dec 16;113(6):1510-1522

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Inhibitory mechanisms of decoy receptor 3 in cecal ligation and puncture-induced sepsis.

Su J, Chen W, Zhou F, Li R, Tong Z, Wu S, Ye Z, Zhang Y, Lin B, Yu X, Guan B, Feng Z, Chen K, Chen Q, Chen L
mBio 2024 Jun 12;15(6):e0052124

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Comprehensive analysis of bulk and single-cell transcriptomic data reveals a novel signature associated with endoplasmic reticulum stress, lipid metabolism, and liver metastasis in pancreatic cancer.

Liu X, Ren B, Fang Y, Ren J, Wang X, Gu M, Zhou F, Xiao R, Luo X, You L, Zhao Y
Journal of translational medicine 2024 Apr 29;22(1):393

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Codelivery of TRAIL and Mitomycin C via Liposomes Shows Improved Antitumor Effect on TRAIL-Resistant Tumors.

Chang R, Fu R, Huang Y, Zhang J, Feng C, Wang R, Yan H, Li G, Chu X, Yuan F, Jia D, Li J
Molecular pharmaceutics 2023 Jun 5;20(6):2864-2875

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A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury.

Yang C, Xu H, Yang D, Xie Y, Xiong M, Fan Y, Liu X, Zhang Y, Xiao Y, Chen Y, Zhou Y, Song L, Wang C, Peng A, Petersen RB, Chen H, Huang K, Zheng L
Nature communications 2023 Jul 17;14(1):4261

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Evodiamine inhibits ESCC by inducing M-phase cell-cycle arrest via CUL4A/p53/p21 axis and activating noxa-dependent intrinsic and DR4-dependent extrinsic apoptosis.

Zhang L, Li L, Chen X, Yuan S, Xu T, Zhao W, Li M, Wang F, Hoffman RM, Jia L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154493

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Sanggenon C Suppresses Tumorigenesis of Gastric Cancer by Blocking ERK-Drp1-Mediated Mitochondrial Fission.

Chen XJ, Cui QX, Wang GL, Li XL, Zhou XL, Zhao HJ, Zhang MQ, Li MJ, He XJ, Zheng QS, Wang YL, Li D, Hong P
Journal of natural products 2022 Oct 28;85(10):2351-2362

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Fusion of an EGFR-antagonistic affibody enhances the anti-tumor effect of TRAIL to EGFR positive tumors.

Jia D, Wang F, Lu Y, Hu P, Wang R, Li G, Liu R, Li J, Liu H, Fan Q, Yuan F
International journal of pharmaceutics 2022 May 25;620:121746

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Site-Specific Integration of TRAIL in iPSC-Derived Mesenchymal Stem Cells for Targeted Cancer Therapy.

Wang Z, Chen H, Wang P, Zhou M, Li G, Hu Z, Hu Q, Zhao J, Liu X, Wu L, Liang D
Stem cells translational medicine 2022 Mar 31;11(3):297-309

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Long noncoding RNA TANCR promotes γδ T cells activation by regulating TRAIL expression in cis.

Yang C, Feng T, Lin F, Gong T, Yang S, Tao Y, Li H
Cell & bioscience 2020;10:15

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IL13Rα1 protects against rheumatoid arthritis by combating the apoptotic resistance of fibroblast-like synoviocytes.

Yang X, Guo Q, Feng T, Lu Q, Ge L, Pan J, Bi K, Qiao L, Tian L, Xie T, Yao C, Song G, Wang L
Arthritis research & therapy 2020 Aug 8;22(1):184