Tissue expression
Cell line expression
Protein structure
TNNC1
Troponin C1, slow skeletal and cardiac typeTNNC
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
Top validated antibodies |
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Proteintech Group | 13504-1-AP | 5 references | Polyclonal |
WB
EL
ICC
IP
IHC
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Invitrogen Antibodies | 13504-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
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antibodies-online | ABIN395127 | Monoclonal |
WB
EL
IHC
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Cusabio Biotech Co., Ltd | CSB-PA024009LA01HU | Polyclonal |
WB
EL
ICC
IHC |
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HUABIO Research | ER1902-25 | Polyclonal |
WB
ICC
IHC
FC |
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Supportive data in Antibodypedia
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Recommended by provider