Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations [0]
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- Product number
- 607401 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#607401, RRID:AB_2117813
- Product name
- Purified anti-HDAC1
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptides, a.a. 1-5, 433-448, and 467-482
- Description
- HDAC1 (histone deacetylase 1) is a 65 kD member of the Class I histone deacetylase family, similar to the yeast RPD3 protein. This nuclear protein operates in concert with histone acetyltransferases to control core histone acetylation in highly conserved lysine residues. HDAC activity has been associated with transcriptional repression and nucleosomal condensation. HDAC1 can be modified by phosphorylation and sumoylation. HDAC1 has been shown to interact with protein phosphatase 1, Rb, MyoD (muscle cells), and the mSin3a co-repressor complex. The Poly6074 antibody has been shown to be useful for Western blotting of human and mouse HDAC1.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 50 µl
- Storage
- Upon receipt, store frozen at -20° C.
Submitted references Stem cell gene SALL4 suppresses transcription through recruitment of DNA methyltransferases.
Yang J, Corsello TR, Ma Y
The Journal of biological chemistry 2012 Jan 13;287(3):1996-2005
The Journal of biological chemistry 2012 Jan 13;287(3):1996-2005
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