Tissue expression
Cell line expression
Protein structure
HDAC1
Histone deacetylase 1GON-10, HD1, KDAC1, RPD3L1
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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GeneTex | GTX100513 | 13 references | Polyclonal |
WB
ICC
IP
IHC
ChIP
|
|
Proteintech Group | 10197-1-AP | 96 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
|
Invitrogen Antibodies | PA1-860 | 68 references | Polyclonal |
WB
ICC
IP
IHC
ChIP
OA |
|
Novus Biologicals | H00003065-M14 | 1 references | Monoclonal |
WB
EL
ICC
IP
IHC
PLA |
|
Abnova Corporation | H00003065-M14 | 1 references | Monoclonal |
WB
EL
ICC
IHC
PLA
|
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Supportive data in Antibodypedia
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Recommended by provider