Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM03208G - Provider product page
- Provider
- Leading Biology
- Product name
- E2F-1 Antibody
- Antibody type
- Monoclonal
- Description
- Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
- Reactivity
- Human
- Host
- Mouse
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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