Tissue expression
Cell line expression

E2F1

gene product
RBBP3, RBP3 
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Antigen sequence

Conjugate

Epitope

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
1459 antibodies from 48 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
47 antibodies
antibodies-online
527 antibodies
Novus Biologicals
66 antibodies
GeneTex
15 antibodies
Proteintech Group
2 antibodies
Boster Biological Technology
6 antibodies
Biorbyt
77 antibodies
LifeSpan BioSciences, Inc.
213 antibodies
Cusabio Biotech Co., Ltd
11 antibodies
HUABIO Research
1 antibody
OriGene
25 antibodies
Abnova Corporation
7 antibodies
Affinity Biosciences
6 antibodies
Atlas Antibodies
2 antibodies
R&D Systems
1 antibody
Santa Cruz Biotechnology
1 antibody
St John's Laboratory
13 antibodies
NovoPro Bioscience Inc.
5 antibodies
Acris Antibodies GmbH
29 antibodies
Abgent
9 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Aviva Systems Biology
15 antibodies
Signalway Antibody LLC
3 antibodies
Bioworld Technology, Inc
3 antibodies
Abbkine Scientific Co.Ltd.
7 antibodies
QED Bioscience
3 antibodies
Bethyl Laboratories
3 antibodies
Antibodies.com
2 antibodies
Cell Signaling Technology, Inc
1 antibody
NSJ Bioreagents
7 antibodies
RabMAbs
4 antibodies
ProSci
11 antibodies
GenWay
15 antibodies
MyBioSource
22 antibodies
Abbexa
21 antibodies
FabGennix
9 antibodies
Arigo
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
United States Biological
164 antibodies
Creative Biolabs
27 antibodies
Creative Diagnostics
7 antibodies
RayBiotech, Inc.
2 antibodies
Leading Biology
7 antibodies
MilliporeSigma / Merck KGaA
9 antibodies
Abbiotec
1 antibody
EMD Millipore
2 antibodies
Everest Biotech
1 antibody