Tissue expression
Cell line expression
Protein structure

E2F1

E2F transcription factor 1
RBBP3, RBP3 
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]
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1525 antibodies from 48 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
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antibodies-online
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66 antibodies
GeneTex
15 antibodies
Proteintech Group
2 antibodies
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6 antibodies
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111 antibodies
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11 antibodies
HUABIO Research
1 antibody
St John's Laboratory
26 antibodies
OriGene
25 antibodies
Abnova Corporation
7 antibodies
Affinity Biosciences
6 antibodies
Atlas Antibodies
2 antibodies
R&D Systems
1 antibody
Santa Cruz Biotechnology
1 antibody
NovoPro Bioscience Inc.
5 antibodies
Acris Antibodies GmbH
29 antibodies
Abgent
9 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Aviva Systems Biology
15 antibodies
Rockland Immunochemicals, Inc.
1 antibody
Signalway Antibody LLC
3 antibodies
Bioworld Technology, Inc
3 antibodies
Abbkine Scientific Co.Ltd.
7 antibodies
QED Bioscience
3 antibodies
Bethyl Laboratories
3 antibodies
Antibodies.com
2 antibodies
Cell Signaling Technology, Inc
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
7 antibodies
RabMAbs
4 antibodies
ProSci
11 antibodies
GenWay
15 antibodies
MyBioSource
22 antibodies
Abbexa
21 antibodies
FabGennix
9 antibodies
Arigo
1 antibody
United States Biological
164 antibodies
Creative Biolabs
28 antibodies
Creative Diagnostics
7 antibodies
RayBiotech, Inc.
2 antibodies
Leading Biology
7 antibodies
MilliporeSigma / Merck KGaA
9 antibodies
Abbiotec
1 antibody
EMD Millipore
2 antibodies