66515-1-Ig

antibody from Proteintech Group

Targeting: E2F1 RBBP3, RBP3

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

66515-1-Ig

Provider

Proteintech Group

Product name

E2F1 antibody

Antibody type

Monoclonal

Description

KD/KO validated E2F1 antibody (Cat. #66515-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

5D7G8

Vial size

20ul, 150ul

References

Submitted references

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Journal of ethnopharmacology 2024 May 10;325:117805

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RNA m(5)C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer.

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LncRNA LINC01703 promotes the proliferation, migration, and invasion of colorectal cancer by activating PI3K/AKT pathway.

Xu Y, Jia K, Zhao X, Li Y, Zhang Z
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MYC induces CDK4/6 inhibitors resistance by promoting pRB1 degradation.

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Nature communications 2024 Feb 29;15(1):1871

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E2F-mediated POLA2 upregulation is correlated with macrophage infiltration and poor prognosis in hepatocellular carcinoma.

Teng Y, Liu R
Translational cancer research 2024 Apr 30;13(4):1848-1860

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GPC3 Promotes Lung Squamous Cell Carcinoma Progression and HLA-A2-Restricted GPC3 Antigenic Peptide-Modified Dendritic Cell-Induced Cytotoxic T Lymphocytes to Kill Lung Squamous Cell Carcinoma Cells.

Ning J, Ding J, Wang S, Jiang Y, Wang D, Jiang S
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Inhibition of IGF2BP1 attenuates renal injury and inflammation by alleviating m6A modifications and E2F1/MIF pathway.

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International journal of biological sciences 2023;19(2):593-609

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Inhibition of USP10 induces myeloma cell apoptosis by promoting cyclin D3 degradation.

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LncRNA AGPG Confers Endocrine Resistance in Breast Cancer by Promoting E2F1 Activity.

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Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression.

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TRIM28 recruits E2F1 to regulate CBX8-mediated cell proliferation and tumor metastasis of ovarian cancer.

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NCAPD2 promotes breast cancer progression through E2F1 transcriptional regulation of CDK1.

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Cancer science 2023 Mar;114(3):896-907

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FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression.

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TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression.

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N-Acetyl-L-Cysteine Reduces Cervical Carcinogenesis by Promoting Apoptosis.

Guo W, Jing W
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Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer.

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The Journal of biological chemistry 2023 Jan;299(1):102734

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E2F1 combined with LINC01004 super-enhancer to promote hepatocellular carcinoma cell proliferation and metastasis.

Li J, Wang J, Wang Y, Zhao X, Su T
Clinical epigenetics 2023 Jan 31;15(1):17

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Transferrin Receptor-Mediated Iron Uptake Promotes Colon Tumorigenesis.

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Inhibition of Angiogenesis by MiR-524-5p through Suppression of AKT and ERK Activation by Targeting CXCR7 in Colon Cancer Cells.

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Journal of oncology 2022;2022:7224840

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Analysis of regulating activities of 5'-epiequisetin on proliferation, apoptosis, and migration of prostate cancer cells in vitro and in vivo.

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E2F1-mediated GINS2 transcriptional activation promotes tumor progression through PI3K/AKT/mTOR pathway in hepatocellular carcinoma.

Zhang Y, Hao X, Han G, Lu Y, Chen Z, Zhang L, Wu J, Wang X
American journal of cancer research 2022;12(4):1707-1726

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POLD2 is activated by E2F1 to promote triple-negative breast cancer proliferation.

Zhang Z
Frontiers in oncology 2022;12:981329

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Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming.

Zuo S, Wang H, Li L, Pan H, Lu L
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Long non-coding RNA SNHG1 activates glycolysis to promote hepatocellular cancer progression through the miR-326/PKM2 axis.

Wang Y, Yang F, Peng Q, Mei K, He H, Yang Q
The journal of gene medicine 2022 Aug;24(8):e3440

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U2 small nuclear RNA auxiliary factor 2, transcriptionally activated by the transcription factor Dp-1/E2F transcription factor 1 complex, enhances the growth and aerobic glycolysis of leiomyosarcoma cells.

Li Y, Chen S, Zhang X, Zhuo N
Bioengineered 2022 Apr;13(4):10200-10212

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RFWD3 Participates in the Occurrence and Development of Colorectal Cancer via E2F1 Transcriptional Regulation of BIRC5.

Xu F, Xiao Z, Fan L, Ruan G, Cheng Y, Tian Y, Chen M, Chen D, Wei Y
Frontiers in cell and developmental biology 2021;9:675356

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Deletion of p16 accelerates fracture healing in geriatric mice.

Ding Q, Liu H, Liu L, Ma C, Qin H, Wei Y, Ren Y
American journal of translational research 2021;13(10):11107-11125

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FGF14-AS2 accelerates tumorigenesis in glioma by forming a feedback loop with miR-320a/E2F1 axis.

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Journal of Cancer 2021;12(21):6429-6438

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Myricanol Inhibits Platelet Derived Growth Factor-BB-Induced Vascular Smooth Muscle Cells Proliferation and Migration in vitro and Intimal Hyperplasia in vivo by Targeting the Platelet-Derived Growth Factor Receptor-β and NF-κB Signaling.

Fan S, Wang C, Huang K, Liang M
Frontiers in physiology 2021;12:790345

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Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.

Wu J, Li Y, Liu J, Xu Y
The journal of gene medicine 2021 Mar;23(3):e3293

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The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: A whole transcriptome profiling-based analysis.

Li Z, Yin H, Shen Y, Ren M, Xu X
Ecotoxicology and environmental safety 2021 Mar 15;211:111945

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Gypenoside LI arrests the cell cycle of breast cancer in G0/G1 phase by down-regulating E2F1.

Zu ML, Duan Y, Xie JB, Qi YS, Xie P, Borjigidai A, Piao XL
Journal of ethnopharmacology 2021 Jun 12;273:114017

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FOXO1 inhibits prostate cancer cell proliferation via suppressing E2F1 activated NPRL2 expression.

Tang Y, Jiang L, Zhao X, Hu D, Zhao G, Luo S, Du X, Tang W
Cell biology international 2021 Dec;45(12):2510-2520

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High-dose copper activates p53-independent apoptosis through the induction of nucleolar stress in human cell lines.

Chen CH, Chou YT, Yang YW, Lo KY
Apoptosis : an international journal on programmed cell death 2021 Dec;26(11-12):612-627

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Cell division cycle associated 8: A novel diagnostic and prognostic biomarker for hepatocellular carcinoma.

Cui XH, Peng QJ, Li RZ, Lyu XJ, Zhu CF, Qin XH
Journal of cellular and molecular medicine 2021 Dec;25(24):11097-11112

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MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma.

Liu H, Chi Z, Jin H, Yang W
Bioengineered 2021 Dec;12(1):1611-1626

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E2F1 mediated DDX11 transcriptional activation promotes hepatocellular carcinoma progression through PI3K/AKT/mTOR pathway.

Yu Y, Zhao D, Li K, Cai Y, Xu P, Li R, Li J, Chen X, Chen P, Cui G
Cell death & disease 2020 Apr 24;11(4):273

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Augmentation of the therapeutic efficacy of WEE1 kinase inhibitor AZD1775 by inhibiting the YAP-E2F1-DNA damage response pathway axis.

Oku Y, Nishiya N, Tazawa T, Kobayashi T, Umezawa N, Sugawara Y, Uehara Y
FEBS open bio 2018 Jun;8(6):1001-1012

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siRNA Delivery for Control of Cyclin D1 and E2F1 Expression in Crohn's Disease.

Russo I, Carrizzo A, Bochicchio S, Piazza O, Lamberti G, Barba AA, Vecchione C, Zeppa P, Iovino P, Bucci C, Santonicola A, Ciacci C
Translational medicine @ UniSa 2017 Jul;17:22-30