Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN1842252 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human, Rat, Bovine, Porcine
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 5H7
- Vial size
- 100 μL
Submitted references Understanding the role of TDP-43 and FUS/TLS in ALS and beyond.
Dynamic subcellular localization of the Ewing sarcoma proto-oncoprotein and its association with and stabilization of microtubules.
The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response.
Ewing sarcoma protein ewsr1 maintains mitotic integrity and proneural cell survival in the zebrafish embryo.
Expression and subcellular localization of Ewing sarcoma (EWS) protein is affected by the methylation process.
Tyrosine kinase Pyk2 mediates G-protein-coupled receptor regulation of the Ewing sarcoma RNA-binding protein EWS.
Da Cruz S, Cleveland DW
Current opinion in neurobiology 2011 Dec;21(6):904-19
Current opinion in neurobiology 2011 Dec;21(6):904-19
Dynamic subcellular localization of the Ewing sarcoma proto-oncoprotein and its association with and stabilization of microtubules.
Leemann-Zakaryan RP, Pahlich S, Sedda MJ, Quero L, Grossenbacher D, Gehring H
Journal of molecular biology 2009 Feb 13;386(1):1-13
Journal of molecular biology 2009 Feb 13;386(1):1-13
The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response.
Andersson MK, Ståhlberg A, Arvidsson Y, Olofsson A, Semb H, Stenman G, Nilsson O, Aman P
BMC cell biology 2008 Jul 11;9:37
BMC cell biology 2008 Jul 11;9:37
Ewing sarcoma protein ewsr1 maintains mitotic integrity and proneural cell survival in the zebrafish embryo.
Azuma M, Embree LJ, Sabaawy H, Hickstein DD
PloS one 2007 Oct 3;2(10):e979
PloS one 2007 Oct 3;2(10):e979
Expression and subcellular localization of Ewing sarcoma (EWS) protein is affected by the methylation process.
Belyanskaya LL, Delattre O, Gehring H
Experimental cell research 2003 Aug 15;288(2):374-81
Experimental cell research 2003 Aug 15;288(2):374-81
Tyrosine kinase Pyk2 mediates G-protein-coupled receptor regulation of the Ewing sarcoma RNA-binding protein EWS.
Felsch JS, Lane WS, Peralta EG
Current biology : CB 1999 May 6;9(9):485-8
Current biology : CB 1999 May 6;9(9):485-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Blots of whole HeLa cell lysates blotted with ABIN1842252. ABIN1842252 binds strongly and cleanly to a band at about 85kDa. Position at which SDS-PAGE molecular weight standards run is are indicated at left.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- An image of HeLa cell cultures stained with antibody ABIN1842252 (green) and chicken antibody to vimentin CPCA-Vim (red). Blue is a DNA stain, and it is clear that in these cells, EWS is localized along with the DNA in the nucleus.