Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AGTO-G028G - Provider product page
- Provider
- Creative Biolabs
- Product name
- Anti-FGFR3 immunotoxin (scFv)-Gel
- Antibody type
- Monoclonal
- Description
- This immunotoxin was achieved by conjugating/fusing the Anti-FGFR3 scFv to gelonin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to bladder carcinoma cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then, gelonin, like abrin and ricin, inhibits protein synthesis by damaging the 60S subunit of mammalian ribosomes. It was designed for treating bladder carcinoma .
- Reactivity
- Human
- Host
- Mouse
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