FGFR3

gene product
ACH, CD333, CEK2, JTK4
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009]
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643 antibodies from 40 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
220 antibodies
Novus Biologicals
75 antibodies
OriGene
33 antibodies
Biorbyt
32 antibodies
Abnova Corporation
4 antibodies
GeneTex
8 antibodies
Invitrogen Antibodies
11 antibodies
Boster Biological Technology
4 antibodies
Acris Antibodies GmbH
11 antibodies
Cell Signaling Technology, Inc
1 antibody
Santa Cruz Biotechnology
1 antibody
LifeSpan BioSciences, Inc.
69 antibodies
R&D Systems
18 antibodies
NSJ Bioreagents
4 antibodies
Abgent
3 antibodies
Affinity Biosciences
4 antibodies
Aviva Systems Biology
2 antibodies
NovoPro Bioscience Inc.
2 antibodies
ProSci
2 antibodies
Bioworld Technology, Inc
1 antibody
St John's Laboratory
2 antibodies
RabMAbs
6 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Biolabs
33 antibodies
MyBioSource
14 antibodies
Arigo
2 antibodies
United States Biological
34 antibodies
Atlas Antibodies
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
FabGennix
6 antibodies
Spring Bioscience
4 antibodies
Creative Diagnostics
8 antibodies
GenWay
2 antibodies
Abbiotec
1 antibody
RayBiotech, Inc.
3 antibodies
Sigma-Aldrich
2 antibodies
Abbexa
4 antibodies
EMD Millipore
1 antibody
Sino Biological Inc.
1 antibody