Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- A00200 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-FGFR3 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for FGFR 3/FGFR3 detection. Host: Rabbit.Size: 100μl. Tested applications: IHC. Reactive species: Human. FGFR 3/FGFR3 information: Molecular Weight: 87710 MW; Subcellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle. Endoplasmic reticulum. The activated receptor is rapidly internalized and degraded. Detected in intracellular vesicles after internalization of the autophosphorylated receptor; Tissue Specificity: Expressed in brain, kidney and testis. Very low or no expression in spleen, heart, and muscle. In 20- to 22- week old fetuses it is expressed at high level in kidney, lung, small intestine and brain, and to a lower degree in spleen, liver, and muscle. Isoform 2 is detected in epithelial cells. Isoform 1 is not detected in epithelial cells. Isoform 1 and isoform 2 are detected in fibroblastic cells.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μl
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- Store at -20°C for one year, at 4°C for one month. We suggest the antibody be aliquoted into small vials and stored frozen at -20°C upon receiving. Avoid repeated freezing and thawing.
Submitted references Expression of fibroblast growth factor 9 and its receptors in the dentate gyrus of hippocampus in poststroke depression rats.
Fluoride regulates the expression of extracellular matrix HSPG and related signaling pathways FGFR3 and Ihh/PTHrP feedback loop during endochondral ossification.
Li A, Tian J, Yang J, Ren X, Zhou Z, Zhou W
Neuroreport 2021 Mar 3;32(4):321-325
Neuroreport 2021 Mar 3;32(4):321-325
Fluoride regulates the expression of extracellular matrix HSPG and related signaling pathways FGFR3 and Ihh/PTHrP feedback loop during endochondral ossification.
Gao Y, Gui F, Li D, Zhang R, Sun Q, Guo X
Environmental toxicology and pharmacology 2020 Jan;73:103275
Environmental toxicology and pharmacology 2020 Jan;73:103275
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from LOVO cells, using FGFR3 antibody A00200.
- Additional image