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- References [5]
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- Product number
- ABIN359858 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Fibroblast Growth Factor Receptor 3 (FGFR3) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells.
[Typical features of craniofacial growth of the FGFR3-associated coronal synostosis syndrome (so-called Muenke craniosynostosis)].
The thanatophoric dysplasia type II mutation hampers complete maturation of fibroblast growth factor receptor 3 (FGFR3), which activates signal transducer and activator of transcription 1 (STAT1) from the endoplasmic reticulum.
A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript.
Achondroplasia in Turkey is defined by recurrent G380R mutation of the FGFR3 gene.
Sturla LM, Merrick AE, Burchill SA
British journal of cancer 2003 Oct 6;89(7):1276-84
British journal of cancer 2003 Oct 6;89(7):1276-84
[Typical features of craniofacial growth of the FGFR3-associated coronal synostosis syndrome (so-called Muenke craniosynostosis)].
Reinhart E, Eulert S, Bill J, Würzler K, Phan The L, Reuther J
Mund-, Kiefer- und Gesichtschirurgie : MKG 2003 May;7(3):132-7
Mund-, Kiefer- und Gesichtschirurgie : MKG 2003 May;7(3):132-7
The thanatophoric dysplasia type II mutation hampers complete maturation of fibroblast growth factor receptor 3 (FGFR3), which activates signal transducer and activator of transcription 1 (STAT1) from the endoplasmic reticulum.
Lievens PM, Liboi E
The Journal of biological chemistry 2003 May 9;278(19):17344-9
The Journal of biological chemistry 2003 May 9;278(19):17344-9
A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript.
Santra M, Zhan F, Tian E, Barlogie B, Shaughnessy J Jr
Blood 2003 Mar 15;101(6):2374-6
Blood 2003 Mar 15;101(6):2374-6
Achondroplasia in Turkey is defined by recurrent G380R mutation of the FGFR3 gene.
Pehlivan S, Ozkinay F, Okutman O, Coğulu O, Ozcan A, Cankaya T, Ulgenalp A
The Turkish journal of pediatrics 2003 Apr-Jun;45(2):99-101
The Turkish journal of pediatrics 2003 Apr-Jun;45(2):99-101
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
