AMM00144G

antibody from Leading Biology

Targeting: XRCC6 D22S671, D22S731, G22P1, KU70, ML8

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM00144G

Provider

Leading Biology

Product name

Ku (p70/p80) (Nuclear Marker) Antibody - With BSA and Azide

Antibody type

Monoclonal

Description

Recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. MAb KU729 recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

KU729

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.