Tissue expression
Cell line expression
Protein structure
XRCC6
X-ray repair cross complementing 6D22S671, D22S731, G22P1, KU70, ML8
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies | 49 references | Monoclonal |
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| Proteintech Group | 29 references | Polyclonal |
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| Novus Biologicals | 2 references | Monoclonal |
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| antibodies-online | 2 references | Monoclonal |
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| GeneTex | 6 references | Polyclonal |
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