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- Antibody Data
- Antigen structure
- References [8]
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- Product number
- 66607-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- KU70,XRCC6 antibody
- Antibody type
- Monoclonal
- Description
- KU70,XRCC6 antibody (Cat. #66607-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3C12D9
- Vial size
- 20ul, 150ul
Submitted references Interactome of intact chromatosome variants with site-specifically ubiquitylated and acetylated linker histone H1.2.
MRE11:p.K464R mutation mediates olaparib resistance by enhancing DNA damage repair in HGSOC.
NAD(+) rescues aging-induced blood-brain barrier damage via the CX43-PARP1 axis.
ITGA2 overexpression inhibits DNA repair and confers sensitivity to radiotherapies in pancreatic cancer.
circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells.
WASH interacts with Ku to regulate DNA double-stranded break repair.
Minimizing adverse effects of Cerenkov radiation induced photodynamic therapy with transformable photosensitizer-loaded nanovesicles.
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation.
Saumer P, Scheffner M, Marx A, Stengel F
Nucleic acids research 2024 Jan 11;52(1):101-113
Nucleic acids research 2024 Jan 11;52(1):101-113
MRE11:p.K464R mutation mediates olaparib resistance by enhancing DNA damage repair in HGSOC.
Zhuang X, Xiao R, Fu Y, Yang B, Fan J, Lu F, Qin T, Yang X, Hu X, Yin J, Li W, Kang X, Chen G, Hu D, Sun C
Cell & bioscience 2023 Sep 27;13(1):178
Cell & bioscience 2023 Sep 27;13(1):178
NAD(+) rescues aging-induced blood-brain barrier damage via the CX43-PARP1 axis.
Zhan R, Meng X, Tian D, Xu J, Cui H, Yang J, Xu Y, Shi M, Xue J, Yu W, Hu G, Li K, Ge X, Zhang Q, Zhao M, Du J, Guo X, Xu W, Gao Y, Yao C, Chen F, Chen Y, Shan W, Zhu Y, Ji L, Pan B, Yu Y, Li W, Zhao X, He Q, Liu X, Huang Y, Liao S, Zhou B, Chui D, Chen YE, Sun Z, Dong E, Wang Y, Zheng L
Neuron 2023 Nov 15;111(22):3634-3649.e7
Neuron 2023 Nov 15;111(22):3634-3649.e7
ITGA2 overexpression inhibits DNA repair and confers sensitivity to radiotherapies in pancreatic cancer.
Zhou C, Li S, Bin K, Qin G, Pan P, Ren D, Zhao Y, Xia W, Chen J, Liu J, Wu H, Zhou Y
Cancer letters 2022 Oct 28;547:215855
Cancer letters 2022 Oct 28;547:215855
circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells.
Li Q, Yao H, Wang Y, Wu Y, Thorne RF, Zhu Y, Wu M, Liu L
Cell reports 2022 Nov 22;41(8):111707
Cell reports 2022 Nov 22;41(8):111707
WASH interacts with Ku to regulate DNA double-stranded break repair.
Wang T, Du XH, Hong Y, Hong X, Fan L, Zhou JW, Sun H, Ge J, Billadeau DD, Deng ZH
iScience 2022 Jan 21;25(1):103676
iScience 2022 Jan 21;25(1):103676
Minimizing adverse effects of Cerenkov radiation induced photodynamic therapy with transformable photosensitizer-loaded nanovesicles.
Qian R, Wang K, Guo Y, Li H, Zhu Z, Huang X, Gong C, Gao Y, Guo R, Yang B, Wang C, Jiang D, Lan X, An R, Gao Z
Journal of nanobiotechnology 2022 Apr 27;20(1):203
Journal of nanobiotechnology 2022 Apr 27;20(1):203
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation.
Wang Y, Fu Z, Li X, Liang Y, Pei S, Hao S, Zhu Q, Yu T, Pei Y, Yuan J, Ye J, Fu J, Xu J, Hong J, Yang R, Hou H, Huang X, Peng C, Zheng M, Xiao Y
Immunity 2021 Apr 13;54(4):632-647.e9
Immunity 2021 Apr 13;54(4):632-647.e9
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