orb1951101

antibody from Biorbyt
Targeting: XRCC6 D22S671, D22S731, G22P1, KU70, ML8
Provider product page for orb1951101
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb1951101 - Provider product page
Provider
Biorbyt
Product name
Ku70 Rabbit mAb [KD Validated]
Antibody type
Recombinant
Description
It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Vial size
50 ul
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
XRCC6 protein structure - orb1951101 shown in red.