ABIN651280

antibody from antibodies-online

Targeting: XRCC6 D22S671, D22S731, G22P1, KU70, ML8

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN651280

Provider

antibodies-online

Product name

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 521-548), (C-Term) antibody

Antibody type

Polyclonal

Description

This antibody is purified through a protein A column, followed by peptide affinity purification.

Reactivity

Human

Host

Rabbit

Epitope

AA 521-548, C-Term

Antibody clone number

RB20806

Vial size

400 μL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Submitted references

Radioresistant cervical cancer shows upregulation of the NHEJ proteins DNA-PKcs, Ku70 and Ku86.

Beskow C, Skikuniene J, Holgersson A, Nilsson B, Lewensohn R, Kanter L, Viktorsson K
British journal of cancer 2009 Sep 1;101(5):816-21

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A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair.

Wang Q, Gao F, Wang T, Flagg T, Deng X
Neoplasia (New York, N.Y.) 2009 Oct;11(10):1012-21

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Ku70 regulates Bax-mediated pathogenesis in laminin-alpha2-deficient human muscle cells and mouse models of congenital muscular dystrophy.

Vishnudas VK, Miller JB
Human molecular genetics 2009 Dec 1;18(23):4467-77

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC