Tissue expression
Cell line expression
Protein structure
LAMTOR3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3MAP2K1IP1, MAPBP, MAPKSP1, MP1, Ragulator3
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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LSBio | LS-C336139 | Polyclonal |
WB
EL
ICC
IHC |
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Proteintech Group | 11937-1-AP | 1 references | Polyclonal |
WB
EL
IHC
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GeneTex | GTX31568 | Polyclonal |
WB
EL
ICC
IHC |
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Boster Biological Technology | A08040 | Polyclonal |
WB
EL
ICC
IHC |
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Biorbyt | orb1239539 | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
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Recommended by provider